周卓，研究员，博士生导师。1998年获得原天津商学院食品工程专业学士学位。2002-2007年在南开大学生物化学专业攻读博士学位，从事免疫细胞功能研究。
     365体育投注_365体育备用-【官方认证】@：引进人才，2023年加入365体育投注_365体育备用-【官方认证】@：。曾于2008年在中国医学科学院病原所进行博士后研究，2012年任助理研究员，2015年升为副研究员，主要研究病毒感染机制。2015-2016在美国西奈山医学院访问研究。2017年进入北京大学任副研究员。

长期从事呼吸道病毒致病机制及抗病毒新策略的研究。研究并发现流感病毒基因组复制转录新模型，揭示新冠病毒感染的天然免疫调控机制，提出病毒性肺炎中的关键病理性因素，以（共同）第一或通讯作者在Cell Host & Microbe, Molecular Cell等杂志发表论文40余篇，多篇论文为ESI高引或F1000推荐，总引用6500余次。主持国家重点研发计划课题、国家科技重大专项子课题、国家自然科学基金面上项目等，获国家科技进步奖二等奖、中华预防医学会科技奖一等奖等。

1. Guo J#, Zhou Z#*, Li R, Xing Z, Zhang L, Zhao S, Wei W, Wang, J*, Deng T*. A genome-wide base-editing screen uncovers a pivotal role of paxillin δ ubiquitination in influenza virus infection. Cell Reports. 2025 Jun 24;44(6):115748. (IF=6.7)

2. Bao Y#, Pan Q#, Xu P#, Liu Z#, Zhang Z, Liu Y, Xu Y, Yu Y, Zhou Z*, Wei W*. Unbiased interrogation of functional lysine residues in human proteome. Mol Cell. 2023 Dec 21;83(24):4614-4632 (IF=14.5, Featured article)

3. Guo S#, Chen Y, Liu J, Zhang X, Liu Z, Zhou Z*, Wei W*. Low-density lipoprotein receptor-related protein 1 is a CROPs-associated receptor for Clostridioides difficile toxin B. Science China Life Sciences. 2022 65(1):107-118. (IF=10.372)

4. Zhou Z#*, Zhang X#, Lei X#, Xiao X#, Jiao T, Ma R, Dong X, Jiang Q, Wang W, Shi Y, Zheng T, Tan Y, Xiang Z, Ren L, Deng T, Jiang Z, Dou Z, Wei W*, Wang J*. Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection. Signal transduction and Targeted Therapy. 2021 6(1):382. (IF=38.104, C100, Featured article)

5. Wang W#, Zhou Z#, Xiao X#, Tian Z, Dong X, Wang C, Li L, Ren L, Lei X*, Xiang Z*, Wang J*. SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation. Cellular & Molecular Immunology. 2021, 18, 945–953 (IF=22.096)

6. Lei X#, Dong X#, Ma R#, Wang W, Xiao X, Tian Z, Wang C, Wang Y, Li L, Ren L, Guo F, Zhao Z, Zhou Z*, Xiang Z*, Wang J*. Activation and evasion of type I interferon responses by SARS-CoV-2. Nature Communications. 2020, 11(1), 3810. (IF=14.919, C100, ESI)

7. Zhou Z#, Ren L#, Zhang L#, Zhong J#, Xiao Y#, Jia Z, Guo L, Yang J, Wang C, Jiang S, Yang D, Zhang G, Li H, Chen F, Xu Y, Chen M, Gao Z, Yang J, Dong J, Liu B, Zhang X, Wang W, He K, Jin Q, Li M*, Wang J*. Heightened innate immune responses in the respiratory tract of COVID-19 cases. Cell Host & Microbe. 2020, 27(10),1-8. (IF=21.023, Cover story, C100, ESI)

8. Qu L#, Yi Z#, Zhu S#, Wang C#, Cao Z#, Zhou Z#, Yuan P#, Yu Y, Tian F, Liu Z, Bao Y, Zhao Y, Wei W*. Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs. Nature Biotechnology. 2019, 37(9):1059-1069. (IF=31.864, F1000)

9. Zhou, Z#, Jia, X#, Xue, Q#, Dou, Z, Ma, Y, Zhao, Z, Jiang, Z, He, B, Jin, Q*, and Wang, J*. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proceedings of the National Academy of Sciences. 2014, 111, E245-E254. (IF=9.809)

10.Zhou, Z#,Cao#, M, Guo, Y#, Zhao, L, Wang, J, Jia, X, Li, J, Wang, C, Gabriel, G, Yi Y, Cui S, Jin Q*, Wang J*, Deng T*. Fragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virus. Nature Communications. 2014, 5, 3259. (IF=10.742, Featured article)